Publicacions de recerca | IRB Barcelona

Title

Year

Research Group

Grups de recerca (Tots)

Systemic and local effect of the Drosophila headcase gene and its role in stress protection of Adult Progenitor Cells

Giannios, P; Casanova, J

Plos Genetics

e1009362 -

2021

MosaicExplorerJ: Interactive stitching of terabyte-size tiled datasets from lightsheet microscopy

Tosi S; Bardia L; Barallobre MJ; Muñoz-Barrutia A; Soto-Montenegro ML; Colombelli J

F1000research

1 -

2021

Regulation of biomolecular condensate dynamics by signaling

Garcia-Cabau, C; Salvatella, X

Current Opinion In Cell Biology

111 -

119

2021

Diversity and versatility of p38 kinase signalling in health and disease

Canovas, B; Nebreda, AR

Nature Reviews Molecular Cell Biology

346 -

366

2021

Unveiling the dimer/monomer propensities of Smad MH1-DNA complexes

Ruiz, L; Kaczmarska, Z; Gomes, T; Aragon, E; Torner, C; Freier, R; Baginski, B; Martin-Malpartida, P; Garrido, ND; Marquez, JA; Cordeiro, TN; Pluta, R; Macias, MJ

Computational And Structural Biotechnology Journal

632 -

646

2021

Centrosomes in asymmetric cell division

Gonzalez, C

Current Opinion In Structural Biology

178 -

182

2021

Clinical Activity of Ripretinib in Patients with Advanced Gastrointestinal Stromal Tumor Harboring Heterogeneous KIT/PDGFRA Mutations in the Phase III INVICTUS Study

Bauer S, Heinrich MC, George S, Zalcberg JR, Serrano C, Gelderblom H, Jones RL, Attia S, D’Amato G, Chi P, Reichardt P, Meade J, Su Y, Ruiz-Soto R, Blay JY,
von Mehren M, Schöffski P.

Clin Cancer Res

6333 -

6342

2021

E3 ubiquitin ligase Atrogin-1 mediates adaptive resistance to KIT-targeted inhibition in gastrointestinal stromal tumor

Alfonso García-Valverde, Jordi Rosell, Sergi Sayols, David Gómez-Peregrina, Daniel F Pilco-Janeta, Iván Olivares-Rivas, Enrique de Álava, Joan Maurel, Jordi Rubió-Casadevall, Anna Esteve, Marta Gut, Claudia Valverde, Jordi Barretina, Joan Carles, George D Demetri, Jonathan A Fletcher, Joaquín Arribas & César Serrano

Oncogene

2021

A gene–environment-induced epigenetic program initiates tumorigenesis

Alonso-Curbelo D, Ho YJ, Burdziak C, Maag JLV, Morris JP 4th, Chandwani R, Chen HA, Tsanov KM, Barriga FM, Luan L, Tasdemir N, Livshits G, Azizi E, Chun J, Wilkinson JE, Mazutis L, Leach SD, Koche R, Pe’er D, Lowe SW.

Nature

2021

Circadian Regulation of Adult Stem Cell Homeostasis and Aging

Benitah, SA; Welz, PS

Cell Stem Cell

817 -

831

2020

BIAFLOWS: A Collaborative Framework to Reproducibly Deploy and Benchmark Bioimage Analysis Workflows

Rubens, U; Mormont, R; Paavolainen, L; Backer, V; Pavie, B; Scholz, LA; Michiels, G; Maska, M; Unay, D; Ball, G; Hoyoux, R; Vandaele, R; Golani, O; Stanciu, SG; Sladoje, N; Paul-Gilloteaux, P; Maree, R; Tosi, S

Patterns

100040 -

2020

Systematic analysis of alterations in the ubiquitin proteolysis system reveals its contribution to driver mutations in cancer

Martinez-Jimenez, F; Muinos, F; Lopez-Arribillaga, E; Lopez-Bigas, N; Gonzalez-Perez, A

Nature Cancer

122 -

2020

Pulmonary glycogen deficiency as a new potential cause of respiratory distress syndrome

Testoni, G; Olmeda, B; Duran, J; López-Rodríguez, E; Aguilera, M; Hernández-Alvarez, MI; Prats, N; Pérez-Gil, J; Guinovart, JJ

Human Molecular Genetics

3554 -

3565

2020

Assembly of the asymmetric human γ-tubulin ring complex by RUVBL1-RUVBL2 AAA ATPase

Zimmermann, F; Serna, M; Ezquerra, A; Fernandez-Leiro, R; Llorca, O; Luders, J

Science Advances

eabe0894 -

2020

In Vivo Reprogramming Ameliorates Aging Features in Dentate Gyrus Cells and Improves Memory in Mice

Rodríguez-Matellán, A; Alcazar, N; Hernández, F; Serrano, M; Avila, J

Stem Cell Reports

1056 -

1066

2020

The dialogue between the ubiquitin-proteasome system and autophagy: Implications in ageing

Sun-Wang, JL; Ivanova, S; Zorzano, A

Ageing Research Reviews

101203 -

2020

Facilitated Diffusion of Proline across Membranes of Liposomes and Living Cells by a Calix[4]pyrrole Cavitand

Martinez-Crespo, Luis; Liang Sun-Wang, Jia; Felipe Sierra, Andres; Aragay, Gemma; Errasti-Murugarren, Ekaitz; Bartoccioni, Paola; Palacin, Manuel; Ballester, P

Chem

3054 -

3070

2020

A fraction of barrier-to-autointegration factor (BAF) associates with centromeres and controls mitosis progression

Torras-Llort, M; Medina-Giró, S; Escudero-Ferruz, P; Lipinszki, Z; Moreno-Moreno, O; Karman, Z; Przewloka, MR; Azorín, F

Commun Biol

454 -

2020

The evolution of relapse of adult T cell acute lymphoblastic leukemia

Sentís, I; Gonzalez, S; Genescà, E; García-Hernández, V; Muiños, F; Gonzalez, C; López-Arribillaga, E; Gonzalez, J; Fernandez-Ibarrondo, L; Mularoni, L; Espinosa, L; Bellosillo, B; Ribera, JM; Bigas, A; Gonzalez-Perez, A; Lopez-Bigas, N

Genome Biology

284 -

2020

ERK1/2 Signaling Induces Upregulation of ANGPT2 and CXCR4 to Mediate Liver Metastasis in Colon Cancer

Urosevic, J; Blasco, MT; Llorente, A; Bellmunt, A; Berenguer-Llergo, A; Guiu, M; Cañellas, A; Fernandez, E; Burkov, I; Clapés, M; Cartanà, M; Figueras-Puig, C; Batlle, E; Nebreda, AR; Gomis, RR

Cancer Research

4668 -

4680

2020

Personalized cancer therapy prioritization based on driver alteration co-occurrence patterns

Mateo, L; Duran-Frigola, M; Gris-Oliver, A; Palafox, M; Scaltriti, M; Razavi, P; Chandarlapaty, S; Arribas, J; Bellet, M; Serra, V; Aloy, P

Genome Medicine

78 -

2020

A compendium of mutational cancer driver genes

Martínez-Jiménez, F; Muiños, F; Sentís, I; Deu-Pons, J; Reyes-Salazar, I; Arnedo-Pac, C; Mularoni, L; Pich, O; Bonet, J; Kranas, H; Gonzalez-Perez, A; Lopez-Bigas, N

Nature Reviews Cancer

555 -

572

2020

Manipulating the Mediator complex to induce naïve pluripotency

Lynch, CJ; Bernad, R; Calvo, I; Serrano, M

Experimental Cell Research

395

112215 -

2020

DNA mismatch repair promotes APOBEC3-mediated diffuse hypermutation in human cancers

Mas-Ponte, D; Supek, F

Nature Genetics

958 -

2020

Induction of lysosome membrane permeabilization as a therapeutic strategy to target pancreatic cancer stem cells

Cash, TP; Alcalá, S; Rico-Ferreira, MD; Hernández-Encinas, E; García, J; Albarrán, MI; Valle, S; Muñoz, J; Martínez-González, S; Blanco-Aparicio, C; Pastor, J; Serrano, M; Sainz, B

Cancers

1790 -

2020

Probing the Kinetic and Thermodynamic Fingerprints of Anti-EGF Nanobodies by Surface Plasmon Resonance

Guardiola, S; Varese, M; Taulés, M; Díaz-Lobo, M; García, J; Giralt, E

Pharmaceuticals

134 -

2020

Matching cell lines with cancer type and subtype of origin via mutational, epigenomic, and transcriptomic patterns

Salvadores, M; Fuster-Tormo, F; Supek, F

Science Advances

eaba1862 -

2020

Self-Eating for Muscle Fitness: Autophagy in the Control of Energy Metabolism

Sebastián, D; Zorzano, A

Developmental Cell

268 -

281

2020

Optimal linker length for small molecule PROTACs that selectively target p38α and p38β for degradation

Donoghue, C; Cubillos-Rojas, M; Gutierrez-Prat, N; Sanchez-Zarzalejo, C; Verdaguer, X; Riera, A; Nebreda, AR

European Journal Of Medicinal Chemistry

201

112451 -

2020

The NEUBIAS Gateway: A hub for bioimage analysis methods and materials

Miura K; Cimini BA; Nørrelykke SF; Louveaux M; Sladoje N; Paul-Gilloteaux P; Colombelli J

F1000research

613 -

2020

Colibactin DNA-damage signature indicates mutational impact in colorectal cancer

Dziubanska-Kusibab, PJ; Berger, H; Battistini, F; Bouwman, BAM; Iftekhar, A; Katainen, R; Cajuso, T; Crosetto, N; Orozco, M; Aaltonen, LA; Meyer, TF

Nature Medicine

1063 -

2020

Extending the small-molecule similarity principle to all levels of biology with the Chemical Checker

Duran-Frigola, M; Pauls, E; Guitart-Pla, O; Bertoni, M; Alcalde, V; Amat, D; Juan-Blanco, T; Aloy, P

Nature Biotechnology

1087 -

2020

Zonation of Ribosomal DNA Transcription Defines a Stem Cell Hierarchy in Colorectal Cancer

Morral, C; Stanisavljevic, J; Hernando-Momblona, X; Mereu, E; Alvarez-Varela, A; Cortina, C; Stork, D; Slebe, F; Turon, G; Whissell, G; Sevillano, M; Merlos-Suárez, A; Casanova-Martí, A; Moutinho, C; Lowe, SW; Dow, LE; Villanueva, A; Sancho, E; Heyn, H; Batlle, E

Cell Stem Cell

845 -

2020

LOBSTER: an environment to design bioimage analysis workflows for large and complex fluorescence microscopy data

Tosi, S; Bardia, L; Filgueira, MJ; Calon, A; Colombelli, J

Bioinformatics

2634 -

2635

2020

A genetic analysis reveals novel histone residues required for transcriptional reprogramming upon stress

Viéitez, C; Martínez-Cebrián, G; Solé, C; Böttcher, R; Potel, CM; Savitski, MM; Onnebo, S; Fabregat, M; Shilatifard, A; Posas, F; de Nadal, E

Nucleic Acids Research

3455 -

3475

2020

The RNA binding protein CPEB2 regulates hormone sensing in mammary gland development and luminal breast cancer

Pascual, R; Martín, J; Salvador, F; Reina, O; Chanes, V; Millanes-Romero, A; Suñer, C; Fernández-Miranda, G; Bartomeu, A; Huang, YS; Gomis, RR; Méndez, R

Science Advances

eaax3868 -

2020

Hog1 activation delays mitotic exit via phosphorylation of Net1

Tognetti, S; Jiménez, J; Viganò, M; Duch, A; Queralt, E; de Nadal, E; Posas, F

Proceedings Of The National Academy Of Sciences Of The United States Of America

117

8924 -

8933

2020

Imaging the Cell Morphological Response to 3D Topography and Curvature in Engineered Intestinal Tissues

Altay, G; Tosi, S; García-Díaz, M; Martínez, E

Frontiers In Bioengineering And Biotechnology

294 -

2020

A reference map of the human binary protein interactome

Luck, K; Kim, DK; Lambourne, L; Spirohn, K; Begg, BE; Bian, WT; Brignall, R; Cafarelli, T; Campos-Laborie, FJ; Charloteaux, B; Choi, D; Cote, AG; Daley, M; Deimling, S; Desbuleux, A; Dricot, A; Gebbia, M; Hardy, MF; Kishore, N; Knapp, JJ; Kovacs, IA; Lemmens, I; Mee, MW; Mellor, JC; Pollis, C; Pons, C; Richardson, AD; Schlabach, S; Teeking, B;...

Nature

580

7803

402 -

2020

4D Genome Rewiring during Oncogene-Induced and Replicative Senescence

Sati, S; Bonev, B; Szabo, Q; Jost, D; Bensadoun, P; Serra, F; Loubiere, V; Papadopoulos, GL; Rivera-Mulia, JC; Fritsch, L; Bouret, P; Castillo, D; Gelpi, JLI; Orozco, M; Vaillant, C; Pellestor, F; Bantignies, F; Marti-Renom, MA; Gilbert, DM; Lemaitre, JM; Cavalli, G

Molecular Cell

522 -

2020

Emergence of chromatin hierarchical loops from protein disorder and nucleosome asymmetry

Sridhar, A; Farr, SE; Portella, G; Schlick, T; Orozco, M; Collepardo-Guevara, R

Proceedings Of The National Academy Of Sciences Of The United States Of America

117

7216 -

7224

2020

Synthesis and Application of 3-Bromo-1,2,4,5-Tetrazine for Protein Labeling to Trigger Click-to-Release Biorthogonal Reactions

Ros, E; Bellido, M; Verdaguer, X; de Pouplana, LR; Riera, A