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Recerca

A l'avantguarda de la biomedicina

Publicacions de recerca

Grups de recerca (Tots)
Biomarker candidates for progression and clinical management of COVID-19 associated pneumonia at time of admission
Calvet, J; Berenguer-Llergo, A; Gay, M; Massanella, M; Domingo, P; Llop, M; Sánchez-Jiménez, E; Arévalo, M; Carrillo, J; Albiñana, N; Arauz-Garofalo, G; Orellana, C; Delgado, JF; Serrano, A; Llobell, A; Graell, E; García-Manrique, M; Moreno, M; Galisteo, C; Casado, E; Navarro, N; Gómez, A; Garcia-Cirera, S; Rusiñol, M; Costa, E; Clotet, B;...
Scientific Reports
12
1
640 -
-
2022
HTSDSF Explorer, A Novel Tool to Analyze High-throughput DSF Screenings: HTSDSF Explorer, a tool for DSF screenings
Martin-Malpartida, P; Hausvik, E; Underhaug, J; Torner, C; Martinez, A; Macias, MJ
Journal Of Molecular Biology
434
11
167372 -
-
2022
Multi-laboratory experiment PME11 for the standardization of phosphoproteome analysis
Colome, N; Abian, J; Aloria, K; Arizmendi, JM; Barcelo-Batllori, S; Braga-Lagache, S; Burlet-Schiltz, O; Carrascal, M; Casal, JI; Chicano-Galvez, E; Chiva, C; Clemente, LF; Elortza, F; Estanyol, JM; Fernandez-Irigoyen, J; Fernandez-Puente, P; Fidalgo, MJ; Froment, C; Fuentes, M; Fuentes-Almagro, C; Gay, M; Hainard, A; Heller, M; Hernandez, ML;...
Journal Of Proteomics
251
-
104409 -
-
2022
Overcoming TGF beta-mediated immune evasion in cancer
Tauriello, DVF; Sancho, E; Batlle, E
Nature Reviews Cancer
22
1
25 -
44
2022
Recent Advances in the Enantioselective Synthesis of Chiral Amines via Transition Metal-Catalyzed Asymmetric Hydrogenation
Cabré, A; Verdaguer, X; Riera, A
Chemical Reviews
122
1
269 -
339
2022
Heteroplasmy of wild type mitochondrial DNA variants in mice causes metabolic heart disease with pulmonary hypertension and frailty
Lechuga-Vieco AV
Circulation
2022
Metabolism of tissue macrophages in homeostasis and pathology
Wculek SK#, Dunphy G, Heras-Murillo I, Mastrangelo A, Sancho D#
(#) Corresponding author
Cellular and Molecular Immunology
19(3):384-408
2022
AutoScanJ: A Suite of ImageJ Scripts for Intelligent Microscopy
Tosi, S; Lladó, A; Bardia, L; Rebollo, E; Godo, A; Stockinger, P; Colombelli, J
Frontiers In Bioinformatics
1
-
627626 -
-
2021
In vivo imaging of DNA-bound minichromosome maintenance complex in embryonic mouse cortex
Mougkogianni, M; Kalogeropoulou, A; Giakoumakis, NN; Lygerou, Z; Taraviras, S
Star Protocols
2
1
100234 -
-
2021
The long non-coding RNA landscape of Candida yeast pathogens
Hovhannisyan, H; Gabaldon, T
Nature Communications
12
1
7317 -
-
2021
Narrow mutational signatures drive acquisition of multidrug resistance in the fungal pathogen Candida glabrata
Ksiezopolska, E; Schikora-Tamarit, MA; Beyer, R; Nunez-Rodriguez, JC; Schuller, C; Gabaldon, T
Current Biology
31
23
5314 -
+
2021
Structural basis for substrate specificity of heteromeric transporters of neutral amino acids
Rodriguez, CF; Escudero-Bravo, P; Diaz, L; Bartoccioni, P; Garcia-Martin, C; Gilabert, JG; Boskovic, J; Guallar, V; Errasti-Murugarren, E; Llorca, O; Palacin, M
Proceedings Of The National Academy Of Sciences Of The United States Of America
118
49
e2113573118 -
-
2021
Dietary palmitic acid promotes a prometastatic memory via Schwann cells
Pascual, G; Dominguez, D; Elosua-Bayes, M; Beckedorff, F; Laudanna, C; Bigas, C; Douillet, D; Greco, C; Symeonidi, A; Hernandez, I; Gil, SR; Prats, N; Bescos, C; Shiekhattar, R; Amit, M; Heyn, H; Shilatifard, A; Benitah, SA
Nature
599
7885
485 -
+
2021
Dietary palmitic acid promotes a prometastatic memory via Schwann cells
Pascual, G; Dominguez, D; Elosua-Bayes, M; Beckedorff, F; Laudanna, C; Bigas, C; Douillet, D; Greco, C; Symeonidi, A; Hernandez, I; Gil, SR; Prats, N; Bescos, C; Shiekhattar, R; Amit, M; Heyn, H; Shilatifard, A; Benitah, SA
Nature
599
7885
485 -
+
2021
Control of hormone-driven organ disassembly by ECM remodeling and Yorkie-dependent apoptosis
Fraire-Zamora, JJ; Tosi, S; Solon, J; Casanova, J
Current Biology
31
23
5261 -
+
2021
Identification and drug-induced reversion of molecular signatures of Alzheimer's disease onset and progression in App(NL-G-F), App(NL-F), and 3xTg-AD mouse models
Pauls, E; Bayod, S; Mateo, L; Alcalde, V; Juan-Blanco, T; Sanchez-Soto, M; Saido, TC; Saito, T; Berrenguer-Llergo, A; Attolini, CSO; Gay, M; de Oliveira, E; Duran-Frigola, M; Aloy, P
Genome Medicine
13
1
168 -
-
2021
Sub-centrosomal mapping identifies augmin-gamma TuRC as part of a centriole-stabilizing scaffold
Schweizer, N; Haren, L; Dutto, I; Viais, R; Lacasa, C; Merdes, A; Luders, J
Nature Communications
12
1
6042 -
-
2021
Conformational landscape of multidomain SMAD proteins
Gomes, T; Martin-Malpartida, P; Ruiz, L; Aragón, E; Cordeiro, TN; Macias, MJ
Computational And Structural Biotechnology Journal
19
-
5210 -
5224
2021
MK2 degradation as a sensor of signal intensity that controls stress-induced cell fate
Gutierrez-Prat, N; Cubillos-Rojas, M; Canovas, B; Kuzmanic, A; Gupta, J; Igea, A; Llonch, E; Gaestel, M; Nebreda, AR
Proceedings Of The National Academy Of Sciences Of The United States Of America
118
29
e2024562118 -
-
2021
Probing allosteric regulations with coevolution-driven molecular simulations
Colizzi, F; Orozco, M
Science Advances
7
37
eabj0786 -
-
2021
Augmin deficiency in neural stem cells causes p53-dependent apoptosis and aborts brain development
Viais, R; Fariña-Mosquera, M; Villamor-Payà, M; Watanabe, S; Palenzuela, L; Lacasa, C; Lüders, J
Elife
10
-
e67989 -
-
2021
In silico saturation mutagenesis of cancer genes
Muiños, F; Martínez-Jiménez, F; Pich, O; Gonzalez-Perez, A; Lopez-Bigas, N
Nature
596
7872
428 -
+
2021
Proteostasis failure and mitochondrial dysfunction leads to aneuploidy-induced senescence
Joy, J; Barrio, L; Santos-Tapia, C; Romao, D; Giakoumakis, NN; Clemente-Ruiz, M; Milan, M
Developmental Cell
56
14
2043 -
+
2021
The ciliary impact of nonciliary gene mutations
Lovera, M; Lüders, J
Trends In Cell Biology
31
11
876 -
887
2021
Highlights from the 2016-2020 NEUBIAS training schools for Bioimage Analysts: A success story and key asset for analysts and life scientists
Martins GG; Cordelières FP; Miura K; Colombelli J; D'Antuono R; Golani O; Guiet R; Haase R; Klemm AH; Louveaux M; Paul-Gilloteaux P; Tinevez J-Y
F1000research
10
-
334 -
-
2021
Repression of endogenous retroviruses prevents antiviral immune response and is required for mammary gland development
Avgustinova, A; Laudanna, C; Pascual-García, M; Rovira, Q; Djurec, M; Castellanos, A; Urdiroz-Urricelqui, U; Marchese, D; Prats, N; Van Keymeulen, A; Heyn, H; Vaquerizas, JM; Benitah, SA
Cell Stem Cell
28
10
1790 -
+
2021
Identification and selectivity profiling of small-molecule degraders via multi-omics approaches
Scholes, NS; Mayor-Ruiz, C; Winter, GE
Cell Chemical Biology
28
7
1048 -
1060
2021
Human tRNAs with inosine 34 are essential to efficiently translate eukarya-specific low-complexity proteins
Torres, AG; Rodríguez-Escribà, M; Marcet-Houben, M; Vieira, HGS; Camacho, N; Catena, H; Recio, MM; Rafels-Ybern, A; Reina, O; Torres, FM; Pardo-Saganta, A; Gabaldón, T; Novoa, EM; de Pouplana, LR
Nucleic Acids Research
49
12
7011 -
7034
2021
Bioactivity descriptors for uncharacterized chemical compounds
Bertoni, M; Duran-Frigola, M; Badia-i-Mompel, P; Pauls, E; Orozco-Ruiz, M; Guitart-Pla, O; Alcalde, V; Diaz, VM; Berenguer-Llergo, A; Brun-Heath, I; Villegas, N; de Herreros, AG; Aloy, P
Nature Communications
12
1
3932 -
-
2021
Bioimage analysis workflows: Community resources to navigate through a complex ecosystem
Paul-Gilloteaux P; Tosi S; Hériché JK; Gaignard A; Ménager H; Marée R; Baecker V; Klemm A; Kalaš M; Zhang C; Miura K; Colombelli J
F1000research
10
-
320 -
-
2021
LRRC8A-containing chloride channel is crucial for cell volume recovery and survival under hypertonic conditions
Serra, SA; Stojakovic, P; Amat, R; Rubio-Moscardo, F; Latorre, P; Seisenbacher, G; Canadell, D; Böttcher, R; Aregger, M; Moffat, J; de Nadal, E; Valverde, MA; Posas, F
Proceedings Of The National Academy Of Sciences Of The United States Of America
118
23
e2025013118 -
-
2021
Environmental robustness of the global yeast genetic interaction network
Costanzo, M; Hou, J; Messier, V; Nelson, J; Rahman, M; VanderSluis, B; Wang, W; Pons, C; Ross, C; Usaj, M; San Luis, BJ; Shuteriqi, E; Koch, EN; Aloy, P; Myers, CL; Boone, C; Andrews, B
Science
372
6542
589 -
+
2021
Impact of DNA methylation on 3D genome structure
Buitrago, D; Labrador, M; Arcon, JP; Lema, R; Flores, O; Esteve-Codina, A; Blanc, J; Villegas, N; Bellido, D; Gut, M; Dans, PD; Heath, SC; Gut, IG; Heath, IB; Orozco, M
Nature Communications
12
1
3243 -
-
2021
Protamine characterization by top-down proteomics: Boosting proteoform identification with dbscan
Arauz-Garofalo, G; Jodar, M; Vilanova, M; Rodriguez, AD; Castillo, J; Soler-Ventura, A; Oliva, R; Vilaseca, M; Gay, M
Proteomes
9
2
21 -
-
2021
The ubiquitin-proteasome system and autophagy: self-digestion for metabolic health
Sun-Wang, JL; Yarritu-Gallego, A; Ivanova, S; Zorzano, A
Trends In Endocrinology And Metabolism
32
8
594 -
608
2021
Structures of the germline-specific Deadhead and thioredoxin T proteins from Drosophila melanogaster reveal unique features among thioredoxins
Freier, R; Aragon, E; Pluta, R; Martin-Malpartida, P; Ruiz, L; Condeminas, M; Gonzalez, C; Macias, MJ
Iucrj
8
Pt 2
281 -
294
2021
Dissection of two routes to naive pluripotency using different kinase inhibitors
Martinez-Val, A; Lynch, CJ; Calvo, I; Ximenez-Embun, P; Garcia, F; Zarzuela, E; Serrano, M; Munoz, J
Nature Communications
12
1
1863 -
-
2021
Report The Upd3 cytokine couples inflammation to maturation defects in Drosophila
Romao, D; Muzzopappa, M; Barrio, L; Milan, M
Current Biology
31
8
1780 -
+
2021
Furan warheads for covalent trapping of weak protein-protein interactions: cross-linking of thymosin beta 4 to actin
Miret-Casals, L; Vannecke, W; Hoogewijs, K; Arauz-Garofalo, G; Gay, M; Díaz-Lobo, M; Vilaseca, M; Ampe, C; Van Troys, M; Madder, A
Chemical Communications
57
49
6054 -
6057
2021
The tumour suppressor brain tumour (Brat) regulates linker histone dBigH1 expression in the Drosophila female germline and the early embryo
Climent-Cantó, P; Carbonell, A; Tamirisa, S; Henn, L; Pérez-Montero, S; Boros, IM; Azorín, F
Open Biology
11
5
200408 -
-
2021
Stability of Imprinting and Differentiation Capacity in Naïve Human Cells Induced by Chemical Inhibition of CDK8 and CDK19
Bernad, R; Lynch, CJ; Urdinguio, RG; Attolini, CSO; Fraga, MF; Serrano, M
Cells
10
4
876 -
-
2021
Quality control of protein reagents for the improvement of research data reproducibility
de Marco, A; Berrow, N; Lebendiker, M; Garcia-Alai, M; Knauer, SH; Lopez-Mendez, B; Matagne, A; Parret, A; Remans, K; Uebel, S; Raynal, B
Nature Communications
12
1
2795 -
-
2021
Intrinsically disordered proteins and biomolecular condensates as drug targets
Biesaga, M; Frigolé-Vivas, M; Salvatella, X
Current Opinion In Chemical Biology
62
-
90 -
100
2021
Loss of the abasic site sensor HMCES is synthetic lethal with the activity of the APOBEC3A cytosine deaminase in cancer cells
Biayna, J; Garcia-Cao, I; Alvarez, MM; Salvadores, M; Espinosa-Carrasco, J; McCullough, M; Supek, F; Stracker, TH
Plos Biology
19
3
e3001176 -
-
2021
The Pseudomonas aeruginosa substrate-binding protein Ttg2D functions as a general glycerophospholipid transporter across the periplasm
Yero, D; Díaz-Lobo, M; Costenaro, L; Conchillo-Solé, O; Mayo, A; Ferrer-Navarro, M; Vilaseca, M; Gibert, I; Daura, X
Commun Biol
4
1
448 -
-
2021
Structure-based design of a Cortistatin analogue with immunomodulatory activity in models of inflammatory bowel disease
Rol, A; Todorovski, T; Martin-Malpartida, P; Escolà, A; Gonzalez-Rey, E; Aragón, E; Verdaguer, X; Vallès-Miret, M; Farrera-Sinfreu, J; Puig, E; Fernández-Carneado, J; Ponsati, B; Delgado, M; Riera, A; Macias, MJ
Nature Communications
12
1
1869 -
-
2021
Nature-inspired dimerization as a strategy to modulate neuropeptide pharmacology exemplified with vasopressin and oxytocin
Dekan, Z; Kremsmayr, T; Keov, P; Godin, M; Teakle, N; Dürrauer, L; Xiang, H; Gharib, D; Bergmayr, C; Hellinger, R; Gay, M; Vilaseca, M; Kurzbach, D; Albericio, F; Alewood, PF; Gruber, CW; Muttenthaler, M
Chemical Science
12
11
4057 -
4062
2021
Candida pathogens induce protective mitochondria-associated type I interferon signalling and a damage-driven response in vaginal epithelial cells
Pekmezovic, M; Hovhannisyan, H; Gresnigt, MS; Iracane, E; Oliveira-Pacheco, J; Siscar-Lewin, S; Seemann, E; Qualmann, B; Kalkreuter, T; Müller, S; Kamradt, T; Mogavero, S; Brunke, S; Butler, G; Gabaldón, T; Hube, B
Nature Microbiology
6
5
643 -
+
2021