Publicacions de recerca | IRB Barcelona

Title

Year

Research Group

The transcriptome of human oocytes is related to age and ovarian reserve

Barragán, M; Pons, J; Ferrer-Vaquer, A; Cornet-Bartolomé, D; Schweitzer, A; Hubbard, J; Auer, H; Rodolosse, A; Vassena, R

Molecular Human Reproduction

535 -

548

2017

Aged Stem Cells Reprogram Their Daily Rhythmic Functions to Adapt to Stress

Solanas, G; Peixoto, FO; Perdiguero, E; Jardí, M; Ruiz-Bonilla, V; Datta, D; Symeonidi, A; Castellanos, A; Welz, PS; Caballero, JM; Sassone-Corsi, P; Muñoz-Cánoves, P; Benitah, SA

Cell

170

678 -

2017

Circadian Reprogramming in the Liver Identifies Metabolic Pathways of Aging

Sato, S; Solanas, G; Peixoto, FO; Bee, L; Symeonidi, A; Schmidt, MS; Brenner, C; Masri, S; Benitah, SA; Sassone-Corsi, P

Cell

170

664 -

2017

Loss of dnmt3a and dnmt3b does not affect epidermal homeostasis but promotes squamous transformation through PPAR-g

Rinaldi, L; Avgustinova, A; Martín, M; Datta, D; Solanas, G; Prats, N; Benitah, SA

Elife

e21697

e21697 -

2017

The dynamic assembly of distinct RNA polymerase i complexes modulates rDNA transcription

Torreira, E; Louro, JA; Pazos, I; Gonález-Polo, N; Gil-Carton, D; Duran, AG; Tosi, S; Gallego, O; Calvo, O; Fernández-Tornero, C

Elife

e20832

e20832 -

2017

Tetraspanin 6: A pivotal protein of the multiple vesicular body determining exosome release and lysosomal degradation of amyloid precursor protein fragments

Guix, FX; Sannerud, R; Berditchevski, F; Arranz, AM; Horré, K; Snellinx, A; Thathiah, A; Saido, T; Saito, T; Rajesh, S; Overduin, M; Kumar-Singh, S; Radaelli, E; Corthout, N; Colombelli, J; Tosi, S; Munck, S; Salas, IH; Annaert, W; De Strooper, B

Molecular Neurodegeneration

25 -

2017

Structure of the homodimeric androgen receptor ligand-binding domain

Nadal, M; Prekovic, S; Gallastegui, N; Helsen, C; Abella, M; Zielinska, K; Gay, M; Vilaseca, M; Taulès, M; Houtsmuller, AB; van Royen, ME; Claessens, F; Fuentes-Prior, P; Estébanez-Perpiñá, E

Nature Communications

14388

14388 -

2017

Polarized cortical tension drives zebrafish epiboly movements

Hernández-Vega, A; Marsal, M; Pouille, PA; Martín-Blanco, E; Tosi, S; Colombelli, J; Luque, T; Navajas, D; Pagonabarraga, I

Embo Journal

25 -

2017

An in vivo genetic screen in Drosophila identifies the orthologue of human cancer/testis gene SPO11 among a network of targets to inhibit lethal(3)malignant brain tumour growth

Rossi, F; Molnar, C; Hashiyama, K; Heinen, JP; Pampalona, J; Llamazares, S; Reina, J; Hashiyama, T; Rai, M; Pollarolo, G; Fernández-Hernández, I; Gonzalez, C

Open Biology

170156 -

2017

The Germline Linker Histone dBigH1 and the Translational Regulator Bam Form a Repressor Loop Essential for Male Germ Stem Cell Differentiation

Carbonell, A; Pérez-Montero, S; Climent-Cantó, P; Reina, O; Azorín, F

Cell Reports

3178 -

3189

2017

Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors

Martin-Malpartida, P; Batet, M; Kaczmarska, Z; Freier, R; Gomes, T; Aragón, E; Zou, YL; Wang, Q; Xi, QR; Ruiz, L; Vea, A; Márquez, JA; Massagué, J; Macias, MJ

Nature Communications

2070 -

2017

Reduced mutation rate in exons due to differential mismatch repair

Frigola, J; Sabarinathan, R; Mularoni, L; Muiños, F; Gonzalez-Perez, A; López-Bigas, N

Nature Genetics

1684 -

2017

Super-Resolution Microscopy Unveils Dynamic Heterogeneities in Nanoparticle Protein Corona

Feiner-Gracia, N; Beck, M; Pujals, S; Tosi, S; Mandal, T; Buske, C; Linden, M; Albertazzi, L

Small

1701631 -

1701631

2017

Effect of MAF amplification on treatment outcomes with adjuvant zoledronic acid in early breast cancer: a secondary analysis of the international, open-label, randomised, controlled, phase 3 AZURE (BIG 01/04) trial

Coleman, R; Hall, A; Albanell, J; Hanby, A; Bell, R; Cameron, D; Dodwell, D; Marshall, H; Jean-Mairet, J; Tercero, JC; Rojo, F; Gregory, W; Gomis, RR

Lancet Oncology

1543 -

1552

2017

Cancer stem cells revisited

Batlle, E; Clevers, H

Nature Medicine

1124 -

1134

2017

Differential requirements for Tousled-like kinases 1 and 2 in mammalian development

Segura-Bayona, S; Knobel, PA; González-Burón, H; Youssef, SA; Peña-Blanco, A; Coyaud, É; López-Rovira, T; Rein, K; Palenzuela, L; Colombelli, J; Forrow, S; Raught, B; Groth, A; de Bruin, A; Stracker, TH

Cell Death And Differentiation

1872 -

1885

2017

Boundary Dpp promotes growth of medial and lateral regions of the Drosophila wing

Barrio, L; Milán, M

Elife

e22013

e22013 -

2017

Feedback amplification loop drives malignant growth in epithelial tissues

Muzzopappa, M; Murcia, L; Milán, M

Proceedings Of The National Academy Of Sciences Of The United States Of America

114

E7291 -

E7300

2017

Linker histone H1 prevents R-loop accumulation and genome instability in heterochromatin

Bayona-Feliu, A; Casas-Lamesa, A; Reina, O; Bernués, J; Azorín, F

Nature Communications

283 -

2017

Musashi 1 regulates the timing and extent of meiotic mRNA translational activation by promoting the use of specific CPEs

Weill, L; Belloc, E; Castellazzi, CL; Méndez, R

Nature Structural & Molecular Biology

672 -

2017

Lack of Glycogenin Causes Glycogen Accumulation and Muscle Function Impairment

Testoni, G; Duran, J; García-Rocha, M; Vilaplana, F; Serrano, AL; Sebastián, D; López-Soldado, I; Sullivan, MA; Slebe, F; Vilaseca, M; Muñoz-Cánoves, P; Guinovart, JJ

Cell Metabolism

256 -

2017

A genome editing approach to study cancer stem cells in human tumors

Cortina, C; Turon, G; Stork, D; Hernando-Momblona, X; Sevillano, M; Aguilera, M; Tosi, S; Merlos-Suárez, A; Attolini, CSO; Sancho, E; Batlle, E

Embo Molecular Medicine

869 -

879

2017

Mex3a Marks a Slowly Dividing Subpopulation of Lgr5+ Intestinal Stem Cells

Barriga, FM; Montagni, E; Mana, M; Mendez-Lago, M; Hernando-Momblona, X; Sevillano, M; Guillaumet-Adkins, A; Rodriguez-Esteban, G; Buczacki, SJA; Gut, M; Heyn, H; Winton, DJ; Yilmaz, OH; Attolini, CSO; Gut, I; Batlle, E

Cell Stem Cell

801 -

2017

JAK/STAT controls organ size and fate specification by regulating morphogen production and signalling

Recasens-Alvarez, C; Ferreira, A; Milán, M

Nature Communications

13815

13815 -

2017

Structural basis of a histidine-DNA nicking/joining mechanism for gene transfer and promiscuous spread of antibiotic resistance

Pluta, R; Boer, DR; Lorenzo-Díaz, F; Russi, S; Gómez, H; Fernández-López, C; Pérez-Luque, R; Orozco, M; Espinosa, M; Coll, M

Proceedings Of The National Academy Of Sciences Of The United States Of America

114

E6526 -

E6535

2017

Mitochondrial Dynamics Mediated by Mitofusin 1 Is Required for POMC Neuron Glucose-Sensing and Insulin Release Control.

Ramírez, S; Gómez-Valadés, AG; Schneeberger, M; Varela, L; Haddad-Tóvolli, R; Altirriba, J; Noguera, E; Drougard, A; Flores-Martínez, A; Imbernón, M; Chivite, I; Pozo, M; Vidal-Itriago, A; Garcia, A; Cervantes, S; Gasa, R; Nogueiras, R; Gama-Pérez, P; Garcia-Roves, PM; Cano, DA; Knauf, C; Servitja, JM; Horvath, TL; Gomis, R; Zorzano, A; Claret, M

Cell Metabolism

1390 -

2017

Circadian- and UPR-dependent control of CPEB4 mediates a translational response to counteract hepatic steatosis under ER stress

Maillo, C; Martín, J; Sebastián, D; Hernández-Alvarez, M; García-Rocha, M; Reina, O; Zorzano, A; Fernandez, M; Méndez, R

Nature Cell Biology

94 -

105

2017

Targeting metastasis-initiating cells through the fatty acid receptor CD36.

Pascual G, Avgustinova A, Mejetta S, Martín M, Castellanos A, Attolini CS, Berenguer A, Prats N, Toll A, Hueto JA, Bescós C, Di Croce L, Benitah SA

Nature

541

7635

41 -

2017

Targeting metastasis-initiating cells through the fatty acid receptor CD36.

Pascual, G; Avgustinova, A; Mejetta, S; Martín, M; Castellanos, A; Attolini, CSO; Berenguer, A; Prats, N; Toll, A; Hueto, JA; Bescós, C; Di Croce, L; Benitah, SA

Nature

541

7635

41 -

2017

A p53-dependent response limits the viability of mammalian haploid cells

Olbrich T., Mayor-Ruiz C., Vega-Sendino M., Gomez C., Ortega S., Ruiz S. & Fernandez-Capetillo O.

PNAS

114

9367 -

9372

2017

TrapSeq: An RNA sequencing-based pipeline for the identification of genetrap insertions in mammalian cells

Mayor-Ruiz C., Dominguez O., Fernandez-Capetillo O

J Mol Bio

429

2780 -

2789

2017

FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth

Slebe, F; Rojo, F; Vinaixa, M; García-Rocha, M; Testoni, G; Guiu, M; Planet, E; Samino, S; Arenas, EJ; Beltran, A; Rovira, A; Lluch, A; Salvatella, X; Yanes, O; Albanell, J; Guinovart, JJ; Gomis, RR

Nature Communications

11199

11199 -

2016

Epigenetic control of adult stem cell function

Avgustinova, A; Benitah, SA

Nature Reviews Molecular Cell Biology

643 -

658

2016

CPEB4 is regulated during cell cycle by ERK2/Cdk1-mediated phosphorylation and its assembly into liquid-like droplets

Guillén-Boixet, J; Buzon, V; Salvatella, X; Méndez, R

Elife

e19298

e19298 -

2016

Amino acid transport associated to cluster of differentiation 98 heavy chain (CD98HC) is at the cross-road of oxidative stress and amino acid availability

de la Ballina, LR; Cano-Crespo, S; González-Muñoz, E; Bial, S; Estrach, S; Cailleteau, L; Tissot, F; Daniel, H; Zorzano, A; Ginsberg, MH; Palacín, M; Féral, CC

Journal Of Biological Chemistry

291

9700 -

9711

2016

The N-Terminal Phosphorylation of RB by p38 Bypasses Its Inactivation by CDKs and Prevents Proliferation in Cancer Cells

Gubern A; Joaquin M; Marquès M; Maseres P; Garcia-Garcia J; Amat R; González-Nuñez D; Oliva B; Real F; de Nadal E; Posas F

Molecular Cell

25 -

2016

Irreversible inhibitors of the 3C protease of Coxsackie virus through templated assembly of protein-binding fragments

Becker, D; Kaczmarska, Z; Arkona, C; Schulz, R; Tauber, C; Wolber, G; Hilgenfeld, R; Coll, M; Rademann, J

Nature Communications

12761

12761 -

2016

Mfn2 deficiency links age-related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathway

Sebastián, D; Sorianello, E; Segalés, J; Irazoki, A; Ruiz-Bonilla, V; Sala, D; Planet, E; Berenguer-Llergo, A; Muñoz, JP; Sánchez-Feutrie, M; Plana, N; Hernández-Alvarez, MI; Serrano, AL; Palacín, M; Zorzano, A

Embo Journal

1677 -

1693

2016

Optical control of endogenous receptors and cellular excitability using targeted covalent photoswitches

Izquierdo-Serra, Merce; Bautista-Barrufet, Antoni; Trapero, Ana; Garrido-Charles, Aida; Diaz-Tahoces, Ariadna; Camarero, Nuria; Pittolo, Silvia; Valbuena, Sergio; Perez-Jimenez, Ariadna; Gay, Marina; Garcia-Moll, Alejandro; Rodriguez-Escrich, Carles; Lerma, Juan; de la Villa, Pedro; Fernandez, Eduardo; Pericas, Miquel A ; Llebaria, Amadeu; Gorostiza, Pau

Nature Communications

12221

12221 -

2016

Non-centrosomal nucleation mediated by augmin organizes microtubules in post-mitotic neurons and controls axonal microtubule polarity

Sánchez-Huertas, C; Freixo, F; Viais, R; Lacasa, C; Soriano, E; Lüders, J

Nature Communications

12187

12187 -

2016

Sequence Context Influences the Structure and Aggregation Behavior of a PolyQ Tract

Eftekharzadeh, B; Piai, A; Chiesa, G; Mungianu, D; García, J; Pierattelli, R; Felli, IC; Salvatella, X