Publicaciones sobre Investigación

Title

Year

Research Group

Regulation of Claspin by the p38 stress-activated protein kinase protects cells from DNA damage

Ulsamer, A; Martínez-Limón, A; Bader, S; Rodríguez-Acebes, S; Freire, R; Méndez, J; de Nadal, E; Posas, F

Cell Reports

111375 -

111375

2022

Integrating and formatting biomedical data as pre-calculated knowledge graph embeddings in the Bioteque

Fernández-Torras, A; Duran-Frigola, M; Bertoni, M; Locatelli, M; Aloy, P

Nature Communications

5304 -

2022

Comparative analyses of vertebrate CPEB proteins define two subfamilies with coordinated yet distinct functions in post-transcriptional gene regulation

Duran-Arqué, B; Cañete, M; Castellazzi, CL; Bartomeu, A; Ferrer-Caelles, A; Reina, O; Caballé, A; Gay, M; Arauz-Garofalo, G; Belloc, E; Mendez, R

Genome Biology

192 -

2022

Targeted immunotherapy against distinct cancer-associated fibroblasts overcomes treatment resistance in refractory HER2+ breast tumors

Rivas, EI; Linares, J; Zwick, M; Gómez-Llonin, A; Guiu, M; Labernadie, A; Badia-Ramentol, J; Lladó, A; Bardia, L; Pérez-Núñez, I; Martínez-Ciarpaglini, C; Tarazona, N; Sallent-Aragay, A; Garrido, M; Celià-Terrassa, T; Burgués, O; Gomis, RR; Albanell, J; Calon, A

Nature Communications

5310 -

2022

The lysosomal proteome of senescent cells contributes to the senescence secretome

Rovira, M; Sereda, R; Pladevall-Morera, D; Ramponi, V; Marin, I; Maus, M; Madrigal-Matute, J; Díaz, A; García, F; Muñoz, J; Cuervo, AM; Serrano, M

Aging Cell

e13707 -

e13707

2022

Lysine 27 dimethylation of Drosophila linker histone dH1 contributes to heterochromatin organization independently of H3K9 methylation

Bernués, J; Izquierdo-Boulstridge, A; Reina, O; Castejón, L; Fernández-Castañer, E; Leal, N; Guerrero-Pepinosa, N; Bonet-Costa, C; Vujatovic, O; Climent-Cantó, P; Azorín, F

Nucleic Acids Research

9212 -

9225

2022

Oxidative Stress Is Associated with Overgrowth in Drosophila l(3)mbt Mutant Imaginal Discs

Climent-Cantó, P; Molnar, C; Santabárbara-Ruiz, P; Prieto, C; Abril, JF; Serras, F; Gonzalez, C

Cells

2542 -

2022

Large-scale analyses of the X chromosome in 2,354 infertile men discover recurrently affected genes associated with spermatogenic failure

Riera-Escamilla, A; Vockel, M; Nagirnaja, L; Xavier, MJ; Carbonell, A; Moreno-Mendoza, D; Pybus, M; Farnetani, G; Rosta, V; Cioppi, F; Friedrich, C; Oud, MS; van der Heijden, GW; Soave, A; Diemer, T; Ars, E; Sánchez-Curbelo, J; Kliesch, S; O'Bryan, MK; Ruiz-Castañe, E; Azorín, F; Veltman, JA; Aston, KI; Conrad, DF; Tüttelmann, F; Krausz, C

American Journal Of Human Genetics

109

1458 -

1471

2022

DNAffinity: a machine-learning approach to predict DNA binding affinities of transcription factors

Barissi, S; Sala, A; Wieczór, M; Battistini, F; Orozco, M

Nucleic Acids Research

9105 -

9114

2022

Discovering the drivers of clonal hematopoiesis

Pich, O; Reyes-Salazar, I; Gonzalez-Perez, A; Lopez-Bigas, N

Nature Communications

4267 -

2022

Discovery and Validation of Clinically Relevant Long Non-Coding RNAs in Colorectal Cancer

Snyder, M; Iraola-Guzmán, S; Saus, E; Gabaldón, T

Cancers

3866 -

2022

A single WNT enhancer drives specification and regeneration of the Drosophila wing

Gracia-Latorre, E; Pérez, L; Muzzopappa, M; Milán, M

Nature Communications

4794 -

2022

TP53-dependent toxicity of CRISPR/Cas9 cuts is differential across genomic loci and can confound genetic screening

Alvarez, MM; Biayna, J; Supek, F

Nature Communications

4520 -

2022

PerSVade: personalized structural variant detection in any species of interest

Schikora-Tamarit, MA; Gabaldón, T

Genome Biology

175 -

2022

The impact of rare germline variants on human somatic mutation processes

Vali-Pour, M; Lehner, B; Supek, F

Nature Communications

3724 -

2022

Mitochondrial RNA modifications shape metabolic plasticity in metastasis

Delaunay, S; Pascual, G; Feng, BH; Klann, K; Behm, M; Hotz-Wagenblatt, A; Richter, K; Zaoui, K; Herpel, E; Munch, C; Dietmann, S; Hess, J; Benitah, SA; Frye, M

Nature

607

7919

593 -

2022

Mitochondrial RNA modifications shape metabolic plasticity in metastasis

Delaunay, S; Pascual, G; Feng, BH; Klann, K; Behm, M; Hotz-Wagenblatt, A; Richter, K; Zaoui, K; Herpel, E; Munch, C; Dietmann, S; Hess, J; Benitah, SA; Frye, M

Nature

607

7919

593 -

2022

Mex3a marks drug-tolerant persister colorectal cancer cells that mediate relapse after chemotherapy

Alvarez-Varela, A; Novellasdemunt, L; Barriga, FM; Hernando-Momblona, X; Canellas-Socias, A; Cano-Crespo, S; Sevillano, M; Cortina, C; Stork, D; Morral, C; Turon, G; Slebe, F; Jimenez-Gracia, L; Caratu, G; Jung, P; Stassi, G; Heyn, H; Tauriello, DVF; Mateo, L; Tejpar, S; Sancho, E; Attolini, CSO; Batlle, E

Nature Cancer

1052 -

2022

BioExcel Building Blocks Workflows (BioBB-Wfs), an integrated web-based platform for biomolecular simulations

Bayarri, G; Andrio, P; Orozco, M; Gelpí, JL

Nucleic Acids Research

W99 -

W107

2022

Chasing molecular glue degraders: screening approaches

Domostegui A, Nieto-Barrado L, Perez-Lopez C, Mayor-Ruiz C

Chemical Society Reviews

5498 -

5517

2022

Chasing molecular glue degraders: screening approaches

Domostegui, A; Nieto-Barrado, L; Perez-Lopez, C; Mayor-Ruiz, C

Chemical Society Reviews

5498 -

5517

2022

Conformational ensemble of the TNF-derived peptide solnatide in solution

Martin-Malpartida, P; Arrastia-Casado, S; Farrera-Sinfreu, J; Lucas, R; Fischer, H; Fischer, B; Eaton, DC; Tzotzos, S; Macias, MJ

Computational And Structural Biotechnology Journal

2082 -

2090

2022

Citizen-science reveals changes in the oral microbiome in Spain through age and lifestyle factors

Willis, JR; Saus, E; Iraola-Guzman, S; Ksiezopolska, E; Cozzuto, L; Bejarano, LA; Andreu-Somavilla, N; Alloza-Trabado, M; Blanco, A; Puig-Sola, A; Broglio, E; Carolis, C; Ponomarenko, J; Hecht, J; Gabaldón, T

Npj Biofilms And Microbiomes

38 -

2022

Natural killer cells act as an extrinsic barrier for in vivo reprogramming

Melendez, E; Chondronasiou, D; Mosteiro, L; de Villarreal, JM; Fernandez-Alfara, M; Lynch, CJ; Grimm, D; Real, FX; Alcami, J; Climent, N; Pietrocola, F; Serrano, M

Development

149

dev200361 -

2022

Mammalian PERIOD2 regulates H2A.Z incorporation in chromatin to orchestrate circadian negative feedback

Tartour, K; Andriani, F; Folco, EG; Letkova, D; Schneider, R; Saidi, I; Sato, T; Welz, PS; Benitah, SA; Allier, C; Padmanabhan, K

Nature Structural & Molecular Biology

549 -

2022

Mutational signatures are markers of drug sensitivity of cancer cells

Levati, J; Salvadores, M; Fuster-Tormo, F; Supek, F

Nature Communications

2926 -

2022

Macrophage inflammation resolution requires CPEB4-directed offsetting of mRNA degradation

Suñer, C; Sibilio, A; Martín, J; Castellazzi, CL; Reina, O; Dotu, I; Caballé, A; Rivas, E; Calderone, V; Díez, J; Nebreda, AR; Méndez, R

Elife

e75873 -

2022

Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors

Herpers, B; Eppink, B; James, MI; Cortina, C; Canellas-Socias, A; Boj, SF; Hernando-Momblona, X; Glodzik, D; Roovers, RC; van de Wetering, M; Bartelink-Clements, C; Zondag-van der Zande, V; Mateos, JG; Yan, K; Salinaro, L; Basmeleh, A; Fatrai, S; Maussang, D; van Bueren, JJL; Chicote, I; Serna, G; Cabellos, L; Ramirez, L; Nuciforo, P; Salazar, R;...

Nature Cancer

418 -

2022

The LEGO® brick road to open science and biotechnology

Boulter, E; Colombelli, J; Henriques, R; Feral, CC

Trends In Biotechnology

1073 -

1087

2022

Pathway-specific effects of ADSL deficiency on neurodevelopment

Dutto, I; Gerhards, J; Herrera, A; Souckova, O; Skopova, V; Smak, JA; Junza, A; Yanes, O; Boeckx, C; Burkhalter, MD; Zikanova, M; Pons, S; Philipp, M; Luders, J; Stracker, TH

Elife

e70518

e70518 -

2022

Multi-omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming

Chondronasiou, D; Gill, D; Mosteiro, L; Urdinguio, RG; Berenguer, A; Aguilera, M; Durand, S; Aprahamian, F; Nirmalathasan, N; Abad, M; Martin-Herranz, DE; Otto-Attolini, CS; Prats, N; Kroemer, G; Fraga, MF; Reik, W; Serrano, M

Aging Cell

e13578 -

2022

Immune translational control by CPEB4 regulates intestinal inflammation resolution and colorectal cancer development

Sibilio, A; Suñner, C; Fernández-Alfara, M; Martín, J; Berenguer, A; Calon, A; Chanes, V; Millanes-Romero, A; Fernández-Miranda, G; Batlle, E; Fernández, M; Méndez, R

Iscience

103790 -

2022

Functional analysis of TLK2 variants and their proximal interactomes implicates impaired kinase activity and chromatin maintenance defects in their pathogenesis

Pavinato, L; Villamor-Payà, M; Sanchiz-Calvo, M; Andreoli, C; Gay, M; Vilaseca, M; Arauz-Garofalo, G; Ciolfi, A; Bruselles, A; Pippucci, T; Prota, V; Carli, D; Giorgio, E; Radio, FC; Antona, V; Giuffrè, M; Ranguin, K; Colson, C; De Rubeis, S; Dimartino, P; Buxbaum, JD; Ferrero, GB; Tartaglia, M; Martinelli, S; Stracker, TH; Brusco, A

Journal Of Medical Genetics

170 -

179

2022

Biomarker candidates for progression and clinical management of COVID-19 associated pneumonia at time of admission

Calvet, J; Berenguer-Llergo, A; Gay, M; Massanella, M; Domingo, P; Llop, M; Sánchez-Jiménez, E; Arévalo, M; Carrillo, J; Albiñana, N; Arauz-Garofalo, G; Orellana, C; Delgado, JF; Serrano, A; Llobell, A; Graell, E; García-Manrique, M; Moreno, M; Galisteo, C; Casado, E; Navarro, N; Gómez, A; Garcia-Cirera, S; Rusiñol, M; Costa, E; Clotet, B; Vilaseca, M; Blanco, J; Gratacós, J

Scientific Reports

640 -

2022

HTSDSF Explorer, A Novel Tool to Analyze High-throughput DSF Screenings: HTSDSF Explorer, a tool for DSF screenings

Martin-Malpartida, P; Hausvik, E; Underhaug, J; Torner, C; Martinez, A; Macias, MJ

Journal Of Molecular Biology

434

167372 -

2022

Multi-laboratory experiment PME11 for the standardization of phosphoproteome analysis

Colome, N; Abian, J; Aloria, K; Arizmendi, JM; Barcelo-Batllori, S; Braga-Lagache, S; Burlet-Schiltz, O; Carrascal, M; Casal, JI; Chicano-Galvez, E; Chiva, C; Clemente, LF; Elortza, F; Estanyol, JM; Fernandez-Irigoyen, J; Fernandez-Puente, P; Fidalgo, MJ; Froment, C; Fuentes, M; Fuentes-Almagro, C; Gay, M; Hainard, A; Heller, M; Hernandez, ML; Ibarrola, N; Iloro, I; Kieselbach, T; Lario, A; Locard-Paulet, M; Marina-Ramirez, A; Martin, L; Morato-Lopez, E; Munoz, J; Navajas, R; Odena, MA; Odriozola, L; de Oliveira, E; Paradela, A; Pasquarello, C; de los Rios, V; Ruiz-Romero, C; Sabido, E; del Pino, MS; Sancho, J; Santamaria, E; Schaeffer-Reiss, C; Schneider, J; de la Torre, C; Valero, ML; Vilaseca, M; Wu, S; Wu, LF; de Embun, PX; Canals, F; Corrales, FJ

Journal Of Proteomics

251

104409

104409 -

2022

Overcoming TGF beta-mediated immune evasion in cancer

Tauriello, DVF; Sancho, E; Batlle, E

Nature Reviews Cancer

25 -

2022

Recent Advances in the Enantioselective Synthesis of Chiral Amines via Transition Metal-Catalyzed Asymmetric Hydrogenation

Cabré, A; Verdaguer, X; Riera, A

Chemical Reviews

122

269 -

339

2022

Heteroplasmy of wild type mitochondrial DNA variants in mice causes metabolic heart disease with pulmonary hypertension and frailty

Lechuga-Vieco AV

Circulation

2022

Metabolism of tissue macrophages in homeostasis and pathology

Wculek SK#, Dunphy G, Heras-Murillo I, Mastrangelo A, Sancho D#
(#) Corresponding author

Cellular and Molecular Immunology

19(3):384-408

2022

AutoScanJ: A Suite of ImageJ Scripts for Intelligent Microscopy

Tosi, S; Lladó, A; Bardia, L; Rebollo, E; Godo, A; Stockinger, P; Colombelli, J

Frontiers In Bioinformatics

627626 -

2021

In vivo imaging of DNA-bound minichromosome maintenance complex in embryonic mouse cortex

Mougkogianni, M; Kalogeropoulou, A; Giakoumakis, NN; Lygerou, Z; Taraviras, S

Star Protocols

100234 -

2021

The long non-coding RNA landscape of Candida yeast pathogens

Hovhannisyan, H; Gabaldon, T

Nature Communications

7317 -

2021

Narrow mutational signatures drive acquisition of multidrug resistance in the fungal pathogen Candida glabrata

Ksiezopolska, E; Schikora-Tamarit, MA; Beyer, R; Nunez-Rodriguez, JC; Schuller, C; Gabaldon, T

Current Biology

5314 -

2021

Structural basis for substrate specificity of heteromeric transporters of neutral amino acids

Rodriguez, CF; Escudero-Bravo, P; Diaz, L; Bartoccioni, P; Garcia-Martin, C; Gilabert, JG; Boskovic, J; Guallar, V; Errasti-Murugarren, E; Llorca, O; Palacin, M

Proceedings Of The National Academy Of Sciences Of The United States Of America

118

e2113573118 -

2021

Dietary palmitic acid promotes a prometastatic memory via Schwann cells

Pascual, G; Dominguez, D; Elosua-Bayes, M; Beckedorff, F; Laudanna, C; Bigas, C; Douillet, D; Greco, C; Symeonidi, A; Hernandez, I; Gil, SR; Prats, N; Bescos, C; Shiekhattar, R; Amit, M; Heyn, H; Shilatifard, A; Benitah, SA

Nature

599

7885

485 -

2021

Dietary palmitic acid promotes a prometastatic memory via Schwann cells

Nature

599

7885

485 -

2021

Control of hormone-driven organ disassembly by ECM remodeling and Yorkie-dependent apoptosis