Publicaciones sobre Investigación

Title

Year

Research Group

Highly Enantioselective Iridium-Catalyzed Hydrogenation of Cyclic Enamides

Salomó, E; Orgué, S; Riera, A; Verdaguer, X

Angewandte Chemie (International Ed. Print)

7988 -

7992

2016

EPI-001, A Compound Active against Castration-Resistant Prostate Cancer, Targets Transactivation Unit 5 of the Androgen Receptor

De Mol, E; Fenwick, RB; Phang, CTW; Buzón, V; Szulc, E; de la Fuente, A; Escobedo, A; García, J; Bertoncini, CW; Estébanez-Perpiñá, E; McEwan, IJ; Riera, A; Salvatella, X

Acs Chemical Biology

2499 -

2505

2016

Novel cystine transporter in renal proximal tubule identified as a missing partner of cystinuria-related plasma membrane protein rBAT/SLC3A1

Nagamori, S; Wiriyasermkul, P; Guarch, ME; Okuyama, H; Nakagomi, S; Tadagaki, K; Nishinaka, Y; Bodoy, S; Takafuji, K; Okuda, S; Kurokawa, J; Ohgaki, R; Nunes, V; Palacin, M; Kanai, Y

Proceedings Of The National Academy Of Sciences Of The United States Of America

113

775 -

780

2016

Essential role of the Cdk2 activator RingoA in meiotic telomere tethering to the nuclear envelope

Mikolcevic, P; Isoda, M; Shibuya, H; Barrantes, ID; Igea, A; Suja, JA; Shackleton, S; Watanabe, Y; Nebreda, AR

Nature Communications

11084

11084 -

2016

Sequential Functions of CPEB1 and CPEB4 Regulate Pathologic Expression of Vascular Endothelial Growth Factor and Angiogenesis in Chronic Liver Disease

Calderone, V; Gallego, J; Fernandez-Miranda, G; Garcia-Pras, E; Maillo, C; Berzigotti, A; Mejias, M; Bava, FA; Angulo-Urarte, A; Graupera, M; Navarro, P; Bosch, J; Fernandez, M; Mendez, R

Gastroenterology

150

982 -

2016

Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing

Latorre-Pellicer A; Moreno-Loshuertos R; Lechuga-Vieco, AV

Nature

2016

BRD4 connects super enhancer remodeling to senescence immune surveillance

Tasdemir N*, Banito B*, Roe JS*, Alonso-Curbelo D*, Camiolo M, Tschaharganeh DF, Huang CH, Aksoy O, Bolden JE, Chen CC, Fennell M, Thapar V, Chicas A, Vakoc CV, Lowe SW.
(*) these authors contributed equally

Cancer Discovery

2016

A genome- wide CRISPR screen identifies Cdc25A as a determinant of sensitivity to ATR inhibitors

Ruiz S. (#), Mayor-Ruiz C. (#), Lafarga V., Murga M., Vega-Sendino M., Ortega S., Fernandez-Capetillo O. ( # Equal contribution)

Mol Cell

307 -

313

2016

Designing alternative splicing RNA-seq studies. Beyond generic guidelines

Attolini, CSO; Peña, V; Rossell, D

Bioinformatics

3631 -

3637

2015

Loss of GPR3 reduces the amyloid plaque burden and improves memory in Alzheimer's disease mouse models

Huang, YH; Skwarek-Maruszewska, A; Horre, K; Vandewyer, E; Wolfs, L; Snellinx, A; Saito, T; Radaelli, E; Corthout, N; Colombelli, J; Lo, AC; Van Aerschot, L; Callaerts-Vegh, Z; Trabzuni, D; Bossers, K; Verhaagen, J; Ryten, M; Munck, S; D'Hooge, R; Swaab, DF; Hardy, J; Saido, TC; De Strooper, B; Thathiah, A

Science Translational Medicine

309

309ra164 -

2015

Mitotic cell rounding and epithelial thinning regulate lumen growth and shape

Hoijman, E; Rubbini, D; Colombelli, J; Alsina, B

Nature Communications

7355

7355 -

2015

Self-assembled trityl radical capsules -implications for dynamic nuclear polarization

Marin-Montesinos, I; Paniagua, JC; Vilaseca, M; Urtizberea, A; Luis, F; Feliz, M; Lin, F; Van Doorslaer, S; Pons, M

Physical Chemistry Chemical Physics

5785 -

5794

2015

The stress kinase p38α as a target for cancer therapy

Igea, A; Nebreda, AR

Cancer Research

3997 -

4002

2015

SDS-PAGE analysis of Aβ oligomers is disserving research into Alzheimer's disease: Appealing for ESI-IM-MS

Pujol-Pina, R; Vilaprinyó-Pascual, S; Mazzucato, R; Arcella, A; Vilaseca, M; Orozco, M; Carulla, N

Scientific Reports

14809

14809 -

2015

Studying tumor growth in Drosophila using the tissue allograft method

Rossi, F; Gonzalez, C

Nature Protocols

1525 -

1534

2015

Dally proteoglycan mediates the autonomous and nonautonomous effects on tissue growth caused by activation of the PI3K and TOR pathways

Ferreira, A; Milán, M

Plos Biology

e1002239 -

2015

Loss of Centrobin Enables Daughter Centrioles to Form Sensory Cilia in Drosophila

Gottardo, M; Pollarolo, G; Llamazares, S; Reina, J; Riparbelli, MG; Callaini, G; Gonzalez, C

Current Biology

2319 -

2324

2015

A role for E-cadherin in ensuring cohesive migration of a heterogeneous population of non-epithelial cells

Campbell, K; Casanova, J

Nature Communications

7998

7998 -

2015

H3K4 monomethylation dictates nucleosome dynamics and chromatin remodeling at stress-responsive genes

Nadal-Ribelles M; Mas G; Millán-Zambrano G; Solé C; Ammerer G; Chávez S; Posas F; De Nadal E

Nucleic Acids Research

4937 -

4949

2015

Inosine modifications in human tRNAs are incorporated at the precursor tRNA level

Torres, AG; Piñeyro, D; Rodríguez-Escribà, M; Camacho, N; Reina, O; Saint-Léger, A; Filonava, L; Batlle, E; de Pouplana, LR

Nucleic Acids Research

5145 -

5157

2015

Structural determinants of Smad function in TGF-β signaling

Macias, MJ; Martin-Malpartida, P; Massagué, J

Trends In Biochemical Sciences

296 -

308

2015

DDsk2 regulates H2Bub1 and RNA polymerase II pausing at dHP1c complex target genes

Kessler, R; Tisserand, J; Font-Burgada, J; Reina, O; Coch, L; Attolini, CSO; Garcia-Bassets, I; Azorín, F

Nature Communications

7049

7049 -

2015

Liver glycogen reduces food intake and attenuates obesity in a high-fat diet-fed mouse model

López-Soldado, I; Zafra, D; Duran, J; Adrover, A; Calbó, J; Guinovart, JJ

Diabetes

796 -

807

2015

Stromal gene expression defines poor-prognosis subtypes in colorectal cancer

Calon, A; Lonardo, E; Berenguer-Llergo, A; Espinet, E; Hernando-Momblona, X; Iglesias, M; Sevillano, M; Palomo-Ponce, S; Tauriello, DVF; Byrom, D; Cortina, C; Morral, C; Barceló, C; Tosi, S; Riera, A; Attolini, CSO; Rossell, D; Sancho, E; Batlle, E

Nature Genetics

320 -

U62

2015

In Silico Prescription of Anticancer Drugs to Cohorts of 28 Tumor Types Reveals Targeting Opportunities

Rubio-Perez C; Tamborero D; Schroeder M; Antolín A; Deu-Pons J; Perez-Llamas C; Mestres J; Gonzalez-Perez A; Lopez-Bigas N

Cancer Cell

382 -

396

2015

Asymmetric intermolecular cobalt-catalyzed pauson-khand reaction using a p-stereogenic bis-phosphane

Orgué, S; León, T; Riera, A; Verdaguer, X

Organic Letters

250 -

253

2015

QUIESCENCE Quantitative differences, qualitative outcomes

Pollarolo, G; Gonzalez, C

Elife

e04869

e04869 -

2015

Decrease in Cell Volume Generates Contractile Forces Driving Dorsal Closure

Saias, L; Swoger, J; D'Angelo, A; Hayes, P; Colombelli, J; Sharpe, J; Salbreux, G; Solon, J

Developmental Cell

611 -

621

2015

Enhanced MAF Oncogene Expression and Breast Cancer Bone Metastasis

Pavlovic, M; Arnal-Estapé, A; Rojo, F; Bellmunt, A; Tarragona, M; Guiu, M; Planet, E; Garcia-Albéniz, X; Morales, M; Urosevic, J; Gawrzak, S; Rovira, A; Prat, A; Nonell, L; Lluch, A; Jean-Mairet, J; Coleman, R; Albanell, J; Gomis, RR

Jnci-Journal Of The National Cancer Institute

107

djv256 -

2015

Quantitative analysis of post-translational modifications in human serum transthyretin associated with familial amyloidotic polyneuropathy by targeted LC-MS and intact protein MS

Vilà-Rico M; Colomé-Calls N; Martín-Castel L; Gay M; Azorín S; Vilaseca M; Planas A; Canals F

Journal Of Proteomics

127

pt b

234 -

246

2015

Neutrophils support lung colonization of metastasis-initiating breast cancer cells

Wculek SK, Malanchi I#
(#) Corresponding author

Nature

528(7582):413-7

2015

Hyperactivated endolysosomal trafficking in melanoma

Alonso-Curbelo D, Soengas MS

Oncotarget

2015

RAB7 counteracts PI3K-driven macropinocytosis activated at early stages of melanoma development

Alonso-Curbelo D, Osterloh L, Cañón E, Calvo TG, Martínez-Herranz R, Karras P, Martínez S, et al, [corr. author] Soengas MS.

Oncotarget

2015

Colon cancer cells colonize the lung from established liver metastases through p38 MAPK signalling and PTHLH

Urosevic, J; Garcia-Albéniz, X; Planet, E; Real, S; Céspedes, MV; Guiu, M; Fernandez, E; Bellmunt, A; Gawrzak, S; Pavlovic, M; Mangues, R; Dolado, I; Barriga, FM; Nadal, C; Kemeny, N; Batlle, E; Nebreda, AR; Gomis, RR

Nature Cell Biology

685 -

2014

The transcription factor GATA6 enables self-renewal of colon adenoma stem cells by repressing BMP gene expression

Whissell, G; Montagni, E; Martinelli, P; Hernando-Momblona, X; Sevillano, M; Jung, P; Cortina, C; Calon, A; Abuli, A; Castells, A; Castellvi-Bel, S; Nacht, AS; Sancho, E; Attolini, CSO; Vicent, GP; Real, FX; Batlle, E

Nature Cell Biology

695 -

2014

Neurons have an active glycogen metabolism that contributes to tolerance to hypoxia

Saez, I; Duran, J; Sinadinos, C; Beltran, A; Yanes, O; Tevy, MF; Martinez-Pons, C; Milan, M; Guinovart, JJ

Journal Of Cerebral Blood Flow And Metabolism

945 -

955

2014

Converging axons collectively initiate and maintain synaptic selectivity in a constantly remodeling sensory organ

Pujol-Martí, J; Faucherre, A; Aziz-Bose, R; Asgharsharghi, A; Colombelli, J; Trapani, JG; López-Schier, H

Current Biology

2968 -

2014

Identification and affinity-quantification of ß-amyloid and α-synuclein polypeptides using on-line SAW-biosensor-mass spectrometry

Slamnoiu, S; Vlad, C; Stumbaum, M; Moise, A; Lindner, K; Engel, N; Vilanova, M; Diaz, M; Karreman, C; Leist, M; Ciossek, T; Hengerer, B; Vilaseca, M; Przybylski, M

Journal Of The American Society For Mass Spectrometry

1472 -

1481

2014

Ibf1 and Ibf2 are novel CP190-interacting proteins required for insulator function

Cuartero, S; Fresán, U; Reina, O; Planet, E; Espinàs, ML

Embo Journal

637 -

647

2014

Folding kinetics of WW domains with the united residue force field for bridging microscopic motions and experimental measurements

Zhou, R; Maisuradze, GG; Suñol, D; Todorovski, T; Macias, MJ; Xiao, Y; Scheraga, HA; Czaplewski, C; Liwo, A

Proceedings Of The National Academy Of Sciences Of The United States Of America

111

18243 -

18248

2014

The dynamics of microtubule minus ends in the human mitotic spindle

Lecland, N; Lüders, J

Nature Cell Biology

770 -

U248

2014

A fly trap mechanism provides sequence-specific RNA recognition by CPEB proteins

Afroz, T; Skrisovska, L; Belloc, E; Guillén-Boixet, J; Méndez, R; Allain, FHT

Genes & Development

1498 -

1514

2014

RARRES3 suppresses breast cancer lung metastasis by regulating adhesion and differentiation

Morales, M; Arenas, EJ; Urosevic, J; Guiu, M; Fernández, E; Planet, E; Fenwick, RB; Fernández-Ruiz, S; Salvatella, X; Reverter, D; Carracedo, A; Massagué, J; Gomis, RR

Embo Molecular Medicine

865 -

881

2014

Fenwick, RB; Orellana, L; Esteban-Martín, S; Orozco, M; Salvatella, X

Nature Communications

4070

4070 -

2014

Glycogen accumulation underlies neurodegeneration and autophagy impairment in lafora disease

Duran, J; Gruart, A; García-Rocha, M; Delgado-García, JM; Guinovart, JJ

Human Molecular Genetics

3147 -

3156

2014

Autophagy-regulating TP53INP2 mediates muscle wasting and is repressed in diabetes

Sala, D; Ivanova, S; Plana, N; Ribas, V; Duran, J; Bach, D; Turkseven, S; Laville, M; Vida, H; Karczewska-Kupczewska, M; Kowalska, I; Straczkowski, M; Testar, X; Palacín, M; Sandri, M; Serrano, AL; Zorzano, A

Journal Of Clinical Investigation

124

1914 -

1927

2014

Dual Function of p38α MAPK in Colon Cancer: Suppression of Colitis-Associated Tumor Initiation but Requirement for Cancer Cell Survival

Gupta, J; Barrantes, ID; Igea, A; Sakellariou, S; Pateras, IS; Gorgoulis, VG; Nebreda, AR

Cancer Cell

484 -

500

2014

Structural bases for the interaction and stabilization of the human amino acid transporter LAT2 with its ancillary protein 4F2hc