Davide Carra

A gene–environment-induced epigenetic program initiates tumorigenesis

Alonso-Curbelo D, Ho YJ, Burdziak C, Maag JLV, Morris JP 4th, Chandwani R, Chen HA, Tsanov KM, Barriga FM, Luan L, Tasdemir N, Livshits G, Azizi E, Chun J, Wilkinson JE, Mazutis L, Leach SD, Koche R, Pe’er D, Lowe SW.

Nature

(2021)

Senolytic CAR T cells reverse senescence-associated pathologies

Amor C*, Feucht J*, Leibold J*, Ho Y-J, Zhu C, Alonso-Curbelo D, Mansilla-Soto J, Boyer JA, Li X, Giavridis T, Kulick A, Houlihan S, et al, Sadelain M, Lowe SW.
(*) these authors contributed equally

Nature

(2020)

An in vivo KRAS allelic series reveals distinct phenotypes of common oncogenic variants

Paz Zafra M, Parsons MJ, Kim J, Alonso-Curbelo D, Goswami S, Schatoff EM, Han T, Katti A, Calvo Fernandez MT, Wilkinson JE, Piskounova E and Dow LE.

Cancer Discovery

(2020)

scKINETICS: inference of regulatory velocity with single-cell transcriptomics data

Burdziak, C; Zhao, CJ; Haviv, D; Alonso-Curbelo, D; Lowe, SW; Pe'er, D

Bioinformatics

39

(39 Suppl 1 )

i394 -

i403

(2023)

Epigenetic plasticity cooperates with cell-cell interactions to direct pancreatic tumorigenesis

Burdziak, C; Alonso-Curbelo, D; Walle, T; Reyes, J; Barriga, F; Haviv, D; Xie, YB; Zhao, Z; Zhao, CJ; Chen, HA; Chaudhary, O; Masilionis, I; Choo, ZN; Gao, V; Luan, W; Wuest, A; Ho, YJ; Wei, YH; Quail, DF; Koche, R; Mazutis, L; Chaligné, R; Nawy, T; Lowe, SW; Pe'er, D

Science

380

(6645 )

597 -

+

(2023)

A gene–environment-induced epigenetic program initiates tumorigenesis

Alonso-Curbelo D, Ho YJ, Burdziak C, Maag JLV, Morris JP 4th, Chandwani R, Chen HA, Tsanov KM, Barriga FM, Luan L, Tasdemir N, Livshits G, Azizi E, Chun J, Wilkinson JE, Mazutis L, Leach SD, Koche R, Pe’er D, Lowe SW.

Nature

(2021)

Senolytic CAR T cells reverse senescence-associated pathologies

Amor C*, Feucht J*, Leibold J*, Ho Y-J, Zhu C, Alonso-Curbelo D, Mansilla-Soto J, Boyer JA, Li X, Giavridis T, Kulick A, Houlihan S, et al, Sadelain M, Lowe SW.
(*) these authors contributed equally

Nature

(2020)

An in vivo KRAS allelic series reveals distinct phenotypes of common oncogenic variants

Paz Zafra M, Parsons MJ, Kim J, Alonso-Curbelo D, Goswami S, Schatoff EM, Han T, Katti A, Calvo Fernandez MT, Wilkinson JE, Piskounova E and Dow LE.

Cancer Discovery

(2020)

scKINETICS: inference of regulatory velocity with single-cell transcriptomics data

Burdziak, C; Zhao, CJ; Haviv, D; Alonso-Curbelo, D; Lowe, SW; Pe'er, D

Bioinformatics

39

(39 Suppl 1 )

i394 -

i403

(2023)

Epigenetic plasticity cooperates with cell-cell interactions to direct pancreatic tumorigenesis

Burdziak, C; Alonso-Curbelo, D; Walle, T; Reyes, J; Barriga, F; Haviv, D; Xie, YB; Zhao, Z; Zhao, CJ; Chen, HA; Chaudhary, O; Masilionis, I; Choo, ZN; Gao, V; Luan, W; Wuest, A; Ho, YJ; Wei, YH; Quail, DF; Koche, R; Mazutis, L; Chaligné, R; Nawy, T; Lowe, SW; Pe'er, D

Science

380

(6645 )

597 -

+

(2023)

A gene–environment-induced epigenetic program initiates tumorigenesis

Alonso-Curbelo D, Ho YJ, Burdziak C, Maag JLV, Morris JP 4th, Chandwani R, Chen HA, Tsanov KM, Barriga FM, Luan L, Tasdemir N, Livshits G, Azizi E, Chun J, Wilkinson JE, Mazutis L, Leach SD, Koche R, Pe’er D, Lowe SW.

Nature

(2021)

Dr. Davide Carra

Selected group publications