Unraveling cancer-associated metabolic bottlenecks in vivo

Johannes Zuber is a Senior Group Leader at the Research Institute of Molecular Pathology (IMP) at the Vienna BioCenter (VBC) and an Adjunct Professor at the Medical University in Vienna, Austria. He studied medicine and received a doctorate in molecular cancer research at the Charité Medical School in Berlin, Germany, where he also completed four years of clinical training in hematology and oncology. During his postdoctoral research at Cold Spring Harbor Laboratory (New York, USA) he developed experimentally tractable cancer mouse models and advanced shRNAmir-based screening tools, which he applied to identify and characterize chromatin-associated dependencies. In his own lab, Johannes Zuber and his team develop and apply innovative tools for RNAi- and CRISPR-based screening and time-resolved transcriptomics to identify and functionally characterize dependencies and candidate targets in cancer and tumor-associated immune cells. He received several prestigious grants and awards (e.g. ERC-StG 2013, EMBO-YIP 2014, German Cancer Prize 2016) and has been elected as an EMBO member in 2022.