Begoña Cánovas

Unit:

Cancer Science

Position:

Research Associate

Office:

EM01B53-4-C53

Telephone:

+34 93 40 20596

Email:

begona.canovas@irbbarcelona.org

Research Group

Signalling and Cell Cycle Laboratory

Cáncer

Selected group publications

Optimal linker length for small molecule PROTACs that selectively target p38α and p38β for degradation

Donoghue, C; Cubillos-Rojas, M; Gutierrez-Prat, N; Sanchez-Zarzalejo, C; Verdaguer, X; Riera, A; Nebreda, AR

European Journal Of Medicinal Chemistry

201

(- )

112451 -

(2020)

Requirement for epithelial p38α in KRAS-driven lung tumor progression

Vitos-Faleato, J; Real, SM; Gutierrez-Prat, N; Villanueva, A; Llonch, E; Drosten, M; Barbacid, M; Nebreda, AR

Proceedings Of The National Academy Of Sciences Of The United States Of America

117

(5 )

2588 -

2596

(2020)

Regulation of tumor angiogenesis and mesenchymal–endothelial transition by p38α through TGF-β and JNK signaling

Batlle, R; Andrés, E; Gonzalez, L; Llonch, E; Igea, A; Gutierrez-Prat, N; Berenguer-Llergo, A; Nebreda, AR

Nature Communications

(1 )

3071 -

(2019)

MK2 degradation as a sensor of signal intensity that controls stress-induced cell fate

Gutierrez-Prat, N; Cubillos-Rojas, M; Canovas, B; Kuzmanic, A; Gupta, J; Igea, A; Llonch, E; Gaestel, M; Nebreda, AR

Proceedings Of The National Academy Of Sciences Of The United States Of America

118

(29 )

e2024562118 -

(2021)

Diversity and versatility of p38 kinase signalling in health and disease

Canovas, B; Nebreda, AR

Nature Reviews Molecular Cell Biology

(5 )

346 -

366

(2021)

Optimal linker length for small molecule PROTACs that selectively target p38α and p38β for degradation

Donoghue, C; Cubillos-Rojas, M; Gutierrez-Prat, N; Sanchez-Zarzalejo, C; Verdaguer, X; Riera, A; Nebreda, AR

European Journal Of Medicinal Chemistry

201

(- )

112451 -

(2020)

Requirement for epithelial p38α in KRAS-driven lung tumor progression

Vitos-Faleato, J; Real, SM; Gutierrez-Prat, N; Villanueva, A; Llonch, E; Drosten, M; Barbacid, M; Nebreda, AR

Proceedings Of The National Academy Of Sciences Of The United States Of America

117

(5 )

2588 -

2596

(2020)

Regulation of tumor angiogenesis and mesenchymal–endothelial transition by p38α through TGF-β and JNK signaling

Batlle, R; Andrés, E; Gonzalez, L; Llonch, E; Igea, A; Gutierrez-Prat, N; Berenguer-Llergo, A; Nebreda, AR

Nature Communications

(1 )

3071 -

(2019)

MK2 degradation as a sensor of signal intensity that controls stress-induced cell fate

Gutierrez-Prat, N; Cubillos-Rojas, M; Canovas, B; Kuzmanic, A; Gupta, J; Igea, A; Llonch, E; Gaestel, M; Nebreda, AR

Proceedings Of The National Academy Of Sciences Of The United States Of America

118

(29 )

e2024562118 -

(2021)

Diversity and versatility of p38 kinase signalling in health and disease

Canovas, B; Nebreda, AR

Nature Reviews Molecular Cell Biology

(5 )

346 -

366

(2021)

Optimal linker length for small molecule PROTACs that selectively target p38α and p38β for degradation

Donoghue, C; Cubillos-Rojas, M; Gutierrez-Prat, N; Sanchez-Zarzalejo, C; Verdaguer, X; Riera, A; Nebreda, AR

European Journal Of Medicinal Chemistry

201

(- )

112451 -

(2020)

Dra. Begoña Cánovas