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Structure of TGIF1, attached to DNA.
Scientific - Published in Nucleic Acids Research
Researchers discover a mechanism that inhibits the Smad signalling pathway
TLK inhibition leads to replication stress (green) and extensive DNA damage (red) in cultured cancer cells. Sandra Segura-Bayona, IRB Barcelona.
Innovation - Published in Science Advances
Key role identified for enzymes in DNA replication and sensitivity to chemotherapeutic drugs
Miquel Duran-Frigola, Associate Researcher at the Structural Bioinformatics and Network Biology lab, IRB Barcelona
Innovation - Published in Nature Communications
Acidic pH: the weakness of cancer cells
The figure shows two views, frontal and lateral, of the image obtained by CT of the lungs of a mouse with fibrosis (grey areas) before and after receiving nano-therapy directed at senescent cells. (Guillem Garaulet and Francisca Mulero, CNIO)
Innovation - Published in EMBO Molecular Medicine
Researchers design a nano-carrier to release drugs into damaged cells
Institutional
Mapping tumour development
Diversity is key: metagenomes from different enviroments can predict different types of gene functions (Graphic, F Supek, IRB Barcelona)
Scientific - Published in Microbiome
The depths of the ocean and gut flora unravel the mystery of microbial genes
Intestine of a patient with ulcerative colitis, a chronic inflammatory disease of the intestine. Macrophage marker is shown in green, activated p38 protein in red, and nucleus in blue. Author: Catrin Youssif, IRB Barcelona
Scientific - Published in EMBO Molecular Medicine
A study points to new therapeutic targets for tumours associated with chronic inflammation
Image: CRG
Scientific
Big Data analysis identifies new cancer risk genes
Image: La Pedrera
Institutional
The Barcelona International Youth Science Challenge (BIYSC) will bring together students from the 5 continents

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