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Research Unit on Asymmetric Synthesis News

Institutional
World Cancer Day 2024: Highlights of IRB Barcelona’s cancer research
Scientific
New drug reveals a key mechanism to overcome resistance to protein degraders
Scientific
Hard to drug: Protein droplets reveal new ways to inhibit transcription factors in an aggressive form of prostate cancer
Lead researchers of the projects awarded with the 2022 BIST Ignite Awards: Sara Ddelci and Antoni Riera (left photo), and David Pesquera and Ekaterina Khestanova (right photo).
Institutional
Research projects developing a new drug for breast cancer and materials with novel properties win the BIST Ignite Awards
Family of structural conformers in solution determined by NMR (above). Detail of the key contacts between amino acids (in yellow) that define the characteristics of the active analogue.
Scientific
Towards a new treatment for Crohn's disease and ulcerative colitis
After APP cleavage at the neuronal membrane, Aβ protein self-assembles into 4 or 8 copies adopting an arrangement allowing passage of water and ions (in red) and thus disrupting ion cell homeostasis © Benjamin Bardiaux.
Scientific
A new mechanism of toxicity in Alzheimer's disease 
revealed by the 3D structure of Aβ protein assemblies
Depicted above, (+)-ryanodol is a derivate of a natural compound with intracellular calcium-regulating capacity
Scientific
Building molecular complexity from scratch
Media mentions
Supporting the excellence of outstanding students
Innovation
“Your work as a researcher can directly help or improve people’s situations”
irbbarcelona
Media mentions
Artisans of pharmaceutical agents
Structure of the somatostatina analogue synthesized in Riera's Lab
Scientific
Better than the natural hormone
Media mentions
Interview with PhD student Nuria Aiguabella