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Matrix, DNA and computational biophysics

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The Uruguayan newpaper La Diaria has published an article about recent research done by the Molecular Modelling and Bioinformatics Lab at IRB Barcelona. This team has achieved the first stable simulations of DNA crystals, thus allowing the study of the role of each molecular component in the stability and conformation of said crystals. The article includes quotes by Pablo Dans, a postdoctoral researcher at the centre, about the study: "What we want is to see how 3D DNA folding occurs and understand how it correlates with the activity of a specific gene. This kind of work has a great plus in that you can see the DNA structure inside the nucleus, and you can manipulate it in three dimensions and even in 4D (adding time) using certain visualization programs."

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About IRB Barcelona

The Institute for Research in Biomedicine (IRB Barcelona) pursues a society free of disease. To this end, it conducts multidisciplinary research of excellence to cure cancer and other diseases linked to ageing. It establishes technology transfer agreements with the pharmaceutical industry and major hospitals to bring research results closer to society, and organises a range of science outreach activities to engage the public in an open dialogue. IRB Barcelona is an international centre that hosts 400 researchers and more than 30 nationalities. Recognised as a Severo Ochoa Centre of Excellence since 2011, IRB Barcelona is a CERCA centre and member of the Barcelona Institute of Science and Technology (BIST).