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Research

At the forefront of biomedicine

Dr. Fran Supek

Unit:
Position:
Group Leader
Office:
CL01C74
Telephone:
+34 93 40 39942

ICREA Research Professor, ERC Starting Grant

ICREA
Research Group

Current researcher's video

Selected group publications

TP53-dependent toxicity of CRISPR/Cas9 cuts is differential across genomic loci and can confound genetic screening
Alvarez, MM; Biayna, J; Supek, F
Nature Communications
13
(1 )
4520 -
-
(2022)
The impact of rare germline variants on human somatic mutation processes
Vali-Pour, M; Lehner, B; Supek, F
Nature Communications
13
(1 )
3724 -
-
(2022)
Mutational signatures are markers of drug sensitivity of cancer cells
Levati, J; Salvadores, M; Fuster-Tormo, F; Supek, F
Nature Communications
13
(1 )
2926 -
-
(2022)
Loss of the abasic site sensor HMCES is synthetic lethal with the activity of the APOBEC3A cytosine deaminase in cancer cells
Biayna, J; Garcia-Cao, I; Alvarez, MM; Salvadores, M; Espinosa-Carrasco, J; McCullough, M; Supek, F; Stracker, TH
Plos Biology
19
(3 )
e3001176 -
(2021)
DNA mismatch repair promotes APOBEC3-mediated diffuse hypermutation in human cancers
Mas-Ponte, D; Supek, F
Nature Genetics
52
(9 )
958 -
+
(2020)