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Research

At the forefront of biomedicine

Dr. Jessica Mainez

Jessica Mainez
Unit:
Position:
Lab Manager
Office:
EM01B22
Telephone:
+34 93 40 37026
Research Group

Selected group publications

scKINETICS: inference of regulatory velocity with single-cell transcriptomics data
Burdziak, C; Zhao, CJ; Haviv, D; Alonso-Curbelo, D; Lowe, SW; Pe'er, D
Bioinformatics
39
(39 Suppl 1 )
i394 -
i403
(2023)
Epigenetic plasticity cooperates with cell-cell interactions to direct pancreatic tumorigenesis
Burdziak, C; Alonso-Curbelo, D; Walle, T; Reyes, J; Barriga, F; Haviv, D; Xie, YB; Zhao, Z; Zhao, CJ; Chen, HA; Chaudhary, O; Masilionis, I; Choo, ZN; Gao, V; Luan, W; Wuest, A; Ho, YJ; Wei, YH; Quail, DF; Koche, R; Mazutis, L; Chaligné, R; Nawy, T; Lowe, SW; Pe'er, D
Science
380
(6645 )
597 -
+
(2023)
A gene–environment-induced epigenetic program initiates tumorigenesis
Alonso-Curbelo D, Ho YJ, Burdziak C, Maag JLV, Morris JP 4th, Chandwani R, Chen HA, Tsanov KM, Barriga FM, Luan L, Tasdemir N, Livshits G, Azizi E, Chun J, Wilkinson JE, Mazutis L, Leach SD, Koche R, Pe’er D, Lowe SW.
Nature
(2021)
Senolytic CAR T cells reverse senescence-associated pathologies
Amor C*, Feucht J*, Leibold J*, Ho Y-J, Zhu C, Alonso-Curbelo D, Mansilla-Soto J, Boyer JA, Li X, Giavridis T, Kulick A, Houlihan S, et al, Sadelain M, Lowe SW.
(*) these authors contributed equally
Nature
(2020)
An in vivo KRAS allelic series reveals distinct phenotypes of common oncogenic variants
Paz Zafra M, Parsons MJ, Kim J, Alonso-Curbelo D, Goswami S, Schatoff EM, Han T, Katti A, Calvo Fernandez MT, Wilkinson JE, Piskounova E and Dow LE.
Cancer Discovery
(2020)